Description: About this productProduct InformationPatients who have problems in swallowing encounter difficulties in taking tablets, particularly pediatric and geriatric patients. Such problems can be resolved by means of orodispersible tablets. These tablets disintegrate instantaneously when put on tongue, releasing the drug that dissolves or disperses in the saliva.Metronidazole is active against a wide variety of anaerobic protozoal parasites and anaerobic bacteria.The present study aim to prepare tablets that can rapidly disintegrate in oral cavity (orodispersible), another challenge with this model drug is to mask the bitter taste. Taste masking was achieved by using aminoalkyl methacrylate copolymer (Eudragit E-100) in the different ratio (1:2 and 1:3) by extrusion technique. The IR shows that there was no significant evidence for interaction between drug and polymers. Six formulations were prepared using taste masked granules and different disintegrants (LH-11) and Avicel PH-102 by varying concentration.Product IdentifiersPublisherLAP Gmbh & Company KGISBN-103848442973ISBN-139783848442973eBay Product ID (ePID)128506802Product Key FeaturesFormatTrade PaperbackPublication Year2012LanguageEnglishDimensionsWeight5 OzWidth6in.Height0.2in.Length9in.Additional Product FeaturesAuthorAnupam Jain, Suresh Kumar Sahu, Aditya Nath Pandey
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Item Length: 9in
Item Height: 0.2in
Item Width: 6in
Author: Aditya Nath Pandey, Anupam Jain, Suresh Kumar Sahu
Publication Name: Taste Mask Orodispersible Tablet of Metronidazole
Format: Trade Paperback
Language: English
Publisher: LAP Gmbh & Company KG
Publication Year: 2012
Type: Textbook
Item Weight: 5 Oz
Number of Pages: 88 Pages