Description: New Products and New Areas of Bioprocess Engineering, Paperback by Berovic, M. (CON); Contreras, B. (CON); Dueser, M. (CON); Krieger, N. (CON); Menge, M. (CON), ISBN 3662147106, ISBN-13 9783662147108, Like New Used, Free shipping in the US Today, ergot alkaloids have found widespread clinical use and more than 50 formulations contain natural or semisynthetic ergot alkaloids. They are used in the treatment of uterine atonia, postpartum bleeding, migraine, orthostatic circulatory disturbances, senile cerebral insufficiency, hypertension, hyp- prolactinemia, acromegaly, and Parkinsonism. Recently, new therapeutic - plications have emerged, ., against schizophrenia and for therapeutic usage based on newly discovered antibacterial and cytostatic effects,immunomodu- tory and hypolipemic broad physiological effects of ergot alkaloids are based mostly on their interactions with neurotransmitter receptors on the cells. The presence of “hidden structures’’ resembling some important neu- humoral mediators (., noradrenaline, serotonin, dopamine) in the molecules of ergot alkaloids could explain their interactions with these receptors [1]. Ergot alkaloids are produced by the filamentous fungi of the genus, Claviceps (., Claviceps purpurea – Ergot, Mutterkorn). On the industrial scale these alkaloids were produced mostly by parasitic cultivation (field production of the ergot) till the end of the 1970s. Today this uneconomic method has been - placed by submerged fermentation. Even after a century of research on ergot alkaloids the search still continues for new, more potent and more selective ergot alkaloid derivatives.
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Book Title: New Products and New Areas of Bioprocess Engineering
Number of Pages: VII, 247 Pages
Publication Name: New Products and New Areas of Bioprocess Engineering
Language: English
Publisher: Springer Berlin / Heidelberg
Subject: Biotechnology, Chemistry / Industrial & Technical, Biomedical
Publication Year: 2013
Type: Textbook
Item Weight: 14.2 Oz
Author: B. Contreras
Item Length: 9.3 in
Subject Area: Technology & Engineering, Science
Item Width: 6.1 in
Series: Advances in Biochemical Engineering/Biotechnology Ser.
Format: Trade Paperback
