Description: Biotics Research Butyric-Cal-Mag 60 Capsules Tributyrin Butyrate Gut Postbiotic to Build Probiotics and Microbiome in GUT / Colon Condition is "New". Shipped with USPS First Class. Expiration 12/25 Butyric-Cal-Mag™ supplies Tributyrin, a butyrate generator. Upon breakdown by gut enzymes, it supplies the postbiotic butyrate, the primary fuel of colonic cells. Butyric acid is a naturally-occurring 4-carbon fatty acid formed in the healthy colon from the fermentation of dietary fiber by friendly bacteria Butyric-Cal-Mag™ supplies tributyrin, as ButyraGen™ a butyrate generator. Upon breakdown by gut enzymes, it supplies the postbiotic butyrate, the primary fuel of colonic cells. Butyric acid is a naturally-occurring 4-carbon fatty acid formed in the healthy colon from the fermentation of dietary f iber by friendly bacteria. Butyric-Cal-Mag™ also contains complementary antioxidants in the form of mixed carotenoids (a source of vitamin A), calcium and magnesium. In addition, this product provides pantothenic acid, necessary for the synthesis of acetyl CoA. Inhibition of the acetyl CoA pathway has been associated with impaired butyrate synthesis. ButyraGenTM – Tributyrin Complex ButyraGen™ is an innovative ingredient. With its ability to work as a direct butyrate generator, it is able to produce high levels of butyrate directly in the colon. In pre-clinical studies of ButyraGen™ Tributyrin Complex has been shown to: • Generate butyrate and other short chain fatty acids • Significantly lower gas production when compared to other prebiotics • Help reduce oxidative stress Butyrate, a type of short-chain fatty acid (SCFA), is produced by commensal bacteria in the colon from the fermentation of dietary fiber, primarily indigestible plant polysaccharides and resistant starches. In addition to its well-recognized role as the preferred energy source for colonocytes, butyrate has now been shown to have a much broader physiological role that extends beyond the colon, influencing systemic metabolic and immune function, as well as reducing intestinal permeability and inflammation. Tributyrin contains three butyrate moieties esterified with glycerol, which is rapidly absorbed and hydrolyzed to butyrate when metabolized by pancreatic lipases. Found in honey and dairy products such as butter, tributyrin has several advantages when compared to supplementation with butyrate alone. Tributyrin is more bioavailable, is better tolerated, and allows for significantly higher plasma levels, with approximately three times the serum half-life (demonstrated in animal studies).6 Additionally, in contrast to tributyrin, it is not clear that oral butyrate reaches colonocytes, as most of it is taken up by enterocytes in the proximal intestine. Clinical Benefits† • Butyrate, a short-chain fatty acid (SCFA), is the primary fuel for epithelial cells of the colon and helps to maintain intestinal barrier integrity. • Tributyrin is a highly bioavailable form of butyrate, providing a superior half-life and increase in plasma levels compared to supplementation with sodium butyrate. • The sustained increase in plasma levels of butyrate with tributyrin supplementation may allow for more systemic and epigenetic effects of butyrate. • In addition to maintaining the intestinal barrier and reducing intestinal inflammation, butyrate has also been associated with multiple metabolic effects, and may play a role in weight and glycemic control, as well as supporting insulin metabolism. • Multiple models suggest tributyrin protects the liver and intestinal barrier from a variety of insults, including ethanol and bacterial toxins.
Price: 59.95 USD
Location: Indianapolis, Indiana
End Time: 2024-09-17T04:51:08.000Z
Shipping Cost: N/A USD
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Item Specifics
Restocking Fee: No
Return shipping will be paid by: Buyer
All returns accepted: Returns Accepted
Item must be returned within: 30 Days
Refund will be given as: Money Back
Brand: Biotics
Active Ingredients: Butyric Acid
Formulation: Capsule